Dear Doc and Donna, Can you tell me the difference between a "Natural" progesterone like RX Prometrium compared to bio-identical progesterone? I recommended to a friend, who is having trouble getting pregnant for 2 years now, to try bio-identical progesterone and to contact you. Her doctor told her that Prometrium is a natural progesterone. She has been on that for a couple of months and hasn't had any success. I would love for her to contact you for an appointment. Thanks so much! DM, Chicago
. Dear DM, While promethium is in theory ‘bio-identical’ and plant based, here is its official description:
PROMETRIUM(progesterone, USP) Capsules contain micronized progesterone for oral administration. Progesterone has a molecular weight of 314.47 and a molecular formula of C21H30O2. Progesterone (pregn-4-ene-3, 20-dione) is a white or creamy white, odorless, crystalline powder practically insoluble in water, soluble in alcohol, acetone and dioxane and sparingly soluble in vegetable oils, stable in air, melting between 126° and 131°C. Progesterone is synthesized from a starting material from a plant source and is chemically identical to progesterone of human ovarian origin. PROMETRIUM capsules are available in multiple strengths to afford dosage flexibility for optimum management. PROMETRIUM capsules contain 100 mg or 200 mg micronized progesterone.
The inactive ingredients for PROMETRIUM Capsules 100 mg include: peanut oil NF, gelatin NF, glycerin USP, lecithin NF, titanium dioxide USP, D&C Yellow No. 10, and FD&C Red No. 40.
The inactive ingredients for PROMETRIUM Capsules 200 mg include: peanut oil NF, gelatin NF, glycerin USP, lecithin NF, titanium dioxide USP, D&C Yellow No. 10, and FD&C Yellow No. 6.
As you can read, the additives and fillers are quite a problem. Similar to our compounded thyroid, PureCell compounds come straight from the source (whether plant if possible, or animal if necessary) and are bound with organic ingredients (often hemp protein) and in veggie caps, so they are much more pure and actually a bit more potent.
We appreciate your kind words and hope we can help your friend.
Good health, good day, Dr. Pearson.
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